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Drotin Plus Tablet combines 80 mg of Drotaverine and 500 mg of Paracetamol to effectively relieve pain from irritable bowel syndrome, menstrual cramps, headaches, and muscle spasms. Drotaverine relaxes smooth muscles by inhibiting phosphodiesterase-IV, while Paracetamol reduces pain by blocking prostaglandins. This dual-action formula provides comprehensive relief from both pain and muscle spasms. The tablet should be taken as directed by a physician, with water, without crushing or chewing. It's essential to consult a healthcare provider before use, especially for those with severe liver, kidney, or heart conditions, or if pregnant or breastfeeding.
Ingredients: Contains Drotaverine (80 mg) and Paracetamol (500 mg). Indications: Used for relieving pain due to irritable bowel syndrome, menstrual cramps, headaches, and muscle spasms. Mechanism: Drotaverine relaxes smooth muscles by inhibiting phosphodiesterase-IV, while Paracetamol reduces pain by blocking prostaglandins. Dosage: Typically taken as directed by a physician, with water, without crushing or chewing. Safety: Not recommended for patients with severe liver, kidney, or heart disease. Consult a physician before use, especially for pregnant or breastfeeding women.
DROTIN PLUS TABLET helps manage pain through its combined actions. Drotaverine works by inhibiting phosphodiesterase 4 (PDE4), an enzyme that breaks down cyclic adenosine monophosphate (cAMP). By inhibiting PDE4, Drotaverine increases cAMP levels and reduces calcium uptake by cells, leading to relaxation of smooth muscles. Paracetamol alleviates pain by reducing the production of prostaglandins in the brain and spinal cord. Prostaglandins are chemicals produced in response to injury and certain diseases that contribute to pain.
Take DROTIN PLUS TABLET as directed by your physician. Swallow the tablet whole with a glass of water; do not crush or chew it. Your doctor will determine the appropriate dose based on your age, body weight, and medical condition.
PREGNANCY DROTIN PLUS TABLET should be used with caution during pregnancy. Consult your doctor before taking it. BREASTFEEDING DROTIN PLUS TABLET should be used with caution while breastfeeding. Consult your doctor before taking it. ALCOHOL Avoid alcohol consumption while taking DROTIN PLUS TABLET, as it may increase the risk of liver damage. KIDNEY DROTIN PLUS TABLET is not recommended for use in patients with severe kidney disease. Consult your doctor before taking it. LIVER DROTIN PLUS TABLET is not recommended for use in patients with severe liver disease and should be used with caution in those with liver conditions (including Gilbert’s syndrome or hepatitis). Consult your doctor before taking it. ALLERGY Do not take DROTIN PLUS TABLET if you are allergic to Drotaverine, Paracetamol, or any other ingredients of this medicine. LUNGS DROTIN PLUS TABLET should be used with caution in patients with lung diseases such as asthma. Consult your doctor before taking it. HEART DISEASE DROTIN PLUS TABLET is not recommended for use in patients with severe heart diseases. Consult your doctor before taking it. USE IN PEDIATRICS Your doctor will prescribe the appropriate dose based on your child’s age, body weight, and medical condition. Consult your doctor before giving DROTIN PLUS TABLET to a child. USE IN GERIATRICS DROTIN PLUS TABLET should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before taking it.
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